A Multilevel Intervention With African American Churches to Enhance Adoption of Point-of-Care HIV and Diabetes Testing, 2014–2018
Gina M. Wingood, Danielle Lambert, Tiffaney Renfro, Mohammed Ali, Ralph Joseph DiClemente
American Journal of Public Health - 2019 Feb.
The authors describe a multilevel intervention to enhance adoption of point-of-care HIV and diabetes testing at church health fairs in Atlanta, Georgia.
When Basal Insulin is Not Enough: A Dose Response Relationship Between Insulin Glargine 100 Units/mL (U100) and Glycemic Control
Guillermo E. Umpierrez, Neil Skolnik, Terry Dex, Louise Traylor, Jason Chao, Charles Shaefer
Diabetes, Obesity and Metabolism - 2019 Feb 5.
In this post-hoc analysis, the authors construct a clinicalresponse curve for basal insulin, assessing the impact of increasing doses on glycemic measures, body weight, and hypoglycemia.
A Randomized Controlled Trial on the Safety and Efficacy of Exenatide Therapy for the Inpatient Management of General Medicine and Surgery Patients With Type 2 Diabetes
Maya Fayfman, Rodolfo J. Galindo, Daniel J. Rubin, et al.
Diabetes Care - 2019 Jan 24.
This multicenter, open-label, randomized trial examines the safety and efficacy of exenatide alone or in combination with basal insulin in non–critically ill patients with type 2 diabetes (T2D).
Clinical characteristics and outcomes of symptomatic and asymptomatic hypoglycemia in hospitalized patients with diabetes
Saumeth Cardona, Patricia C. Gomez, Priyathama Vellanki, et al.
BMJ Open Diabetes Research and Care - 2018 Dec 18;6(1):e000607.
The authors determine the clinical characteristics and hospital outcomes of general medicine and surgery patients with symptomatic and asymptomatic hypoglycemia.
Predicting diabetes risk among HIV-positive and HIV-negative women: an assessment of the ADA and FINRISC diabetes risk scores
Karla I. Galaviz, Michael F. Schneider, Phyllis Tien, et al.
AIDS. 2018 Nov 28;32(18):2767-2775.
The authors assess the performance of an adapted American Diabetes Association (ADA) risk score and the concise Finnish Diabetes Risk Score (FINRISC) for predicting type 2 diabetes in women with and at risk of HIV infection.
Glycaemic Efficacy and Safety of Linagliptin compared to Basal-Bolus Insulin Regimen in Patients with Type 2 Diabetes Undergoing Non-Cardiac Surgery: A Multicenter Randomized Clinical Trial
Priyathama Vellanki, Neda Rasouli, David Baldwin, et al.
Diabetes, Obesity and Metabolism - 2018 Nov 20.
The use of incretin-based therapy instead of or complementary to insulin therapy is an active area of research in hospitalized patients with type 2 diabetes (T2D). Here, the authors determine glycaemic efficacy and safety of linagliptin compared to basal-bolus insulin regimen in hospitalized surgical patients with T2D.
Advancing Health Policy and Program Research in Diabetes: Findings from the Natural Experiments for Translation in Diabetes (NEXT-D) Network
Mohammed K. Ali, Frank Wharam, O. Kenrik Duru, et al.
Current Diabetes Reports - 2018 Nov 20;18(12):146.
To advance understanding of the impacts of policies and programs aimed at improving detection, engagement, prevention, and clinical diabetes management in the USA, the authors synthesize findings from a network of studies that use natural experiments to evaluate diabetes health policies and programs.
Self-Efficacy and Diabetes Prevention in Overweight South Asians with Prediabetes
Catherine E. Cioffi, Harish Ranjani, Lisa R. Staimez, Ranjit Mohan Anjana, Viswanathan Mohan, Mary Beth Weber
BMJ Open Diabetes Research & Care - 2018 Oct 15;6(1):e000561
The authors evaluated the effects of a diabetes prevention itervention on self-efficacy (SE) and the associations between SE and diabetes-related outcomes among overweight Asian Indian adults with pre-diabetes in a randomized controlled translational trial (the Diabetes Community Lifestyle Improvement Program, D-CLIP).
Safety and Efficacy of DPP4 Inhibitor and Basal Insulin in Type 2 Diabetes: An Updated Review and Challenging Clinical Scenarios
Fernando Gomez-Peralta, Cristina Abreu, Sara Gomez-Rodriguez, Rafael J. Barranco, and Guillermo E. Umpierrez
Diabetes Therapy - 2018 Oct;9(5):1775-1789
The present review summarizes the extensive evidence on the combination therapy of DPP4 inhibitors and insulin-based regimens in patients with type 2 diabetes. The authors focus their discussion on challenging clinical scenarios including patients with chronic renal impairment, elderly persons and hospitalized patients.
Cost-Effectiveness of a Faith-Based Lifestyle Intervention for Diabetes Prevention among African Americans: A Within-Trial Analysis
Elizabeth C. Rhodes, Eeshwar K. Chandrasekar, Shivani A. Patel, K.M. Venkat Narayan, Thomas V. Joshua, Lovoria B. Williams, Lucy Marion, and Mohammed K. Ali
Diabetes Research and Clinical Practice - 2018 Sep 28;146:85-92
The authors assessed costs and cost-effectiveness of implementing Fit Body and Soul (FBAS), a church-based 18-session lifestyle education intervention for African Americans.
Ethnic Differences in the Prevalence of Diabetes in Underweight and Normal Weight Individuals: The CARRS and NHANES Studies
Unjali P. Gujral, Viswanathan Mohan, Rajendra Pradeepa, Mohan Deepa, Ranjit Mohan Anjana, and K.M. Venkat Narayan
Diabetes Research and Clinical Practice - 2018 Sep 20;146:34-40
Type 2 diabetes in lean individuals has recently come to attention. The assessed type 2 diabetes prevalence and the associated risk factors in underweight and normal weight individuals in two ethnic populations.
Advancing Measurement of Diabetes at the Population Level
Mohammed K. Ali, Karen R. Siegel, Michael Laxy, and Edward W. Gregg
Current Diabetes Reports - 2018 Sep 19;18(11):108
To provide a critical reflection on current diabetes surveillance, the authors provide in-depth discussion about how upstream determinants, prevalence, incidence, and downstream impacts of diabetes are measured in the USA, and the challenges in obtaining valid, accurate, and precise estimates.
Sitagliptin for prevention of stress hyperglycemia in patients without diabetes undergoing general surgery: A pilot randomized study
Maya Fayfman, Georgia Davis, Elizabeth W. Duggan, Maria Urrutia, David Chachkhiani, Joanna Schindler, Francisco J. Pasquel, Rodolfo J. Galindo, Priyathama Vellanki, David Reyes-Umpierrez, Heqiong Wang, and Guillermo E. Umpierrez
Journal of Diabetes and its Complications - 2018 Sep 1. pii: S1056-8727(18)30752-9
The authors investigated if a dipeptidyl peptidase-4 inhibitor, sitagliptin, can prevent perioperative stress hyperglycemia in patients without prior history of diabetes mellitus undergoing general surgery.
Diabetes Among Non-Overweight Individuals: an Emerging Public Health Challenge
Unjali P. Gujral, Mary Beth Weber, Lisa R. Staimez, and K.M. Venkat Narayan
Current Diabetes Reports - 2018 Jul:18(8):60
In this review, the authors discuss the epidemiology of type 2 diabetes in non-overweight adults; pose questions about etiology, pathophysiology, diagnosis, and prognosis; and examine implications for prevention and treatment.
Global Diabetes Prevention Interventions: A Systematic Review and Network Meta-analysis of the Real-World Impact on Incidence, Weight, and Glucose
Karla Ivette Galaviz, Mary Beth Weber, Audrey Straus, Jeehea Sonya Haw, K.M. Venkat Narayan, and Mohammed Kumail Ali
Diabetes Care - 2018 Jul;41(7):1526-1534
The purpose of this study was to synthetize global evidence on the impact of lifestyle modification (LSM) strategies on diabetes incidence and risk factors in one parsimonious model.
The Efficacy and Safety of Co-Administration of Sitagliptin with Metformin in Patients with Type 2 Diabetes at Hospital Discharge
Roma Y. Gianchandani, Francisco J. Pasquel, Daniel J. Rubin, Kathleen M. Dungan, Priyathama Vellanki, Heqiong Wang, Isabel Anzola, Patricia Gomez, Israel Hodish, Sangeeta Lathkar-Pradhan, Jennifer Iyengar, and Guillermo E. Umpierrez
Endocrine Practice - 2018 Jun;24(6):556-564
Few randomized controlled trials have focused on the optimal management of patients with type 2 diabetes (T2D) during the transition from the inpatient to outpatient setting. This multicenter open-label study explored a discharge strategy based on admission hemoglobin A1c (HbA1c) to guide therapy in general medicine and surgery patients with T2D.
Room for Improvement: The HIV–Diabetes Care Continuum Over 15 Years in the Women’s Interagency HIV Study
Jonathan Colasanti, Karla I. Galaviz, C. Christina Mehta, Kartika Palar, Michael F. Schneider, Phyllis Tien, Adaora A. Adimora, et al.
Open Forum Infectious Diseases - 2018 May;5(6)
The authors analyzed cross-sectional data of the Women's Interagency HIV Study (WIHS) from 2001, 2006, and 2015. They estimated the proportions of HIV-positive and HIV-negative women with diabetes who were engaged in care and achieved treatment goals and viral suppression.
A Randomized Controlled Study Comparing a DPP4 Inhibitor (Linagliptin) and Basal Insulin (Glargine) in Patients With Type 2 Diabetes in Long-term Care and Skilled Nursing Facilities: Linagliptin-LTC Trial
Guillermo E. Umpierrez, Saumeth Cardona, David Chachkhiani, Maya Fayfman, Sahebi Saiyed, Heqiong Wang, Priyathama Vellanki, et al.
Journal of the American Medical Directors Association - 2018 May;19(5):399-404
This 6-month open-label randomized controlled trial compared the efficacy and safety of a DPP4 inhibitor (linagliptin) and basal insulin (glargine) in LTC residents with T2DM.
Are the U.S. Territories Lagging Behind in Diabetes Care Practices?
Rachel P. Ogilvie, Shivani A. Patel, K.M. Venkat Narayan, Neil K. Mehta
Primary Care Diabetes - 2018 May;pii:S1751-9918
The authors compare the prevalence and secular trends of four recommended diabetes care practices in the U.S. territories of Guam, Puerto Rico, and the U.S. Virgin Islands to the 50 United States and D.C. ("U.S. States") in 2001-2015.
Dietary Behaviors and Glucose Metabolism in Young Adults at Risk for Type 2 Diabetes
EunSeok Cha, Sudeshna Paul, Betty J. Braxter, Guillermo Umpierrez, Melissa Spezia Faulkner
The Diabetes Educator - 2018 Apr;44(2):158-167
The purpose of the study was to examine the associations between dietary behaviors and glucose metabolism in high-risk young adults to increase the precision of nutrition education to prevent early onset type 2 diabetes (T2D).
The Effect of Continuous Glucose Mointoring in Preventing Inpatient Hypoglycemia in General Wards: The Glucose Telemtery System
Elias K. Spanakis, David L. Levitt, Tariq Siddiqui, Lakshmi G. Singh, Lillian Pinault, John Sorkin, Guillermo E. Umpierrez, Jeffrey C. Fink
Journal of Diabetes Science and Technology - 2018 Jan;12(1):20-25
The aim of this pilot study was to examine whether CGM readings can be successfully transmitted from the bedside to a central monitoring device in the nursing station, and whether a glucose telemetry system can prevent hypoglycemic events.
Declines in the Incidence of Diabetes in the U.S.: Real Progress or Artifact?
Elizabeth Selvin, Mohammed K. Ali
Diabetes Care - 2017 Sep;40(9):1139-1143
The authors present and discuss data that suggest improved detection and changes in screening and diagnostic practices may have resulted in the depletion of the "susceptible population."
Entrenched Obesity in Childhood: Findings from a National Cohort Study
Solveig A. Cunningham, Ashlesha Datar, K. M. Venkat Narayan, Michael R. Kramer
Annals of Epidemiology - 2017 Jul;27(7):435-441
Even one timepoint of obesity measured during the early elementary school years may be an indicator of risk for long-term obesity.
Perioperative Hyperglycemia Management: An Update
Elizabeth W. Duggan, Karen Carlson, Guillermo E. Umpierrez
Anesthesiology - 2017 Mar;126(3):547-560
County-level Contextual Factors Associated with Diabetes Incidence in the United States
Solveig A. Cunningham, Shivani A. Patel, Gloria L. Beckles, Linda S. Geiss, Neil Mehta, Hui Xie, Giuseppina Imperatore
Annals of Epidemiology - 2017 Nov 23. pii: S1047-2797(17)30172-2
This study explores how geographic distribution of diabetes in the US is associated with socioeconomic and built environment characteristics and health-relevant.
Field Epidemiology Training Program (FETP) Investigation Guide
This Field Epidemiology Training Program Investigators Guide was produced by CDC in collaboration with EGDRC, and was led by Dr. Unjali Gujral at Emory.
Incidence of Diabetes after a Partner's Diagnosis
Solveig A. Cunningham, Sara R. Adams, Julie A. Schmittdiel, and Mohammed K. Ali
Preventive Medicine - 2017 Dec;105:52-57
In a cohort study, we examined whether incidence of diabetes was different for individuals with recently diagnosed partners compared to individuals similar on other characteristics but whose partners were never diagnosed with diabetes.
Participation in a National Lifestyle Change Program is Associated with Improved Diabetes Control Outcomes
This research studied the largest clinical lifestyle change program in the United States, the Veteran’s Health Administration’s MOVE! program.
A National Effort to PreventType 2 Diabetes: Participant-Level Evaluation of CDC’s National Diabetes Prevention Program
Elizabeth K. Ely, Stephanie M. Gruss, Elizabeth T. Luman, Edward W. Gregg, Mohammed K. Ali, Kunthea Nhim, Deborah B. Rolka, and Ann L. Albright
Diabetes Care - 2017 Oct; 40(10):1331-1341
This paper assesses participant-level results from the first 4 years of implementation of the National Diabetes Prevention Program (National DPP), a national effort to prevent type 2 diabetes in those at risk through structured lifestyle change programs.
The Stability of Children's Weight Status Over Time, and the Role of Television, Physical Activity, and Diet in Elementary School
Sandra L. Jackson and Solveig A. Cunningham
Preventive Medicine - Vol. 100, July 2017; pp. 229-234
This study examined the effects of weight-related behaviors on subsequent changes in weight during childhood using the Early Childhood Longitudinal Study Kindergarten Cohort (ECLS-K), a nationally representative prospective cohort of children in the United States.
Preventing Disability: The Influence Of Modifiable Risk Factors On State And National Disability Prevalence
Neil K. Mehta, Shivani A. Patel, Mohammed K. Ali, and K. M. Venkat Narayan
Health Affairs - April 2017, Vol. 36, No. 4
This analysis provides a benchmark for national and state-level monitoring of disability levels in the US population over time and across regions. Further understanding of the wide state-level variation in disability and the prevalence of risk factors may also yield important policy insights.
Incidence Trends of Type 1 and Type 2 Diabetes among Youths, 2002–2012
Elizabeth J. Mayer-Davis, Jean M. Lawrence, Lawrence Dolan, Giuseppina Imperatore, et al.
New England Journal of Medicine - 2017, 376:1419-1429
This study concludes that the incidences of both type 1 and type 2 diabetes among youths increased significantly in the 2002–2012 period, particularly among youths of minority racial and ethnic groups.
Relationship Between Prenatal Growth, Postnatal Growth and Childhood Obesity: A Review
E.K. Matthews, Jingkai Wei, and Solveig A. Cunningham
European Journal of Clinical Nutrition - 2017 Aug; 71(8):919-930
This systematic review assesses whether rapid growth during the first two years of life holds different implications for children according to their prenatal growth.
Solveig A. Cunningham, Aleena Mosher, Suzanne E. Judd, Lisa M. Matz, Edmond K. Kabagambe, Claudia S. Moy, and Virginia J. Howard
Journals of Gerontology: Social Sciences; 2017 Feb 10
Among older adults, those who used to, but no longer, drink had higher risks of stroke, especially among women; current light drinkers had the lowest risk of stroke.